Evaluation of Percutaneous Penetration of Natural Rubber Latex Proteins

Evaluation of percutaneous penetration of natural rubber latex proteins.

Latex allergy is recognized worldwide as a serious health risk. To date, exposure assessment and intervention strategies have focused primarily on respiratory protection; this work evaluates the potential role of dermal protein penetration in the development of latex allergy. In vitro penetration models using flow-through diffusion cells and both human surgical specimens and hairless guinea pig...

Natural Rubber Latex Allergy

Natural Rubber Latex Allergy

I n the past 10 years, IgE-mediated allergy to natural rubber latex has become a significant health problem in industrialized countries, especially among health care workers, patients with congenital malformations, and children with a history of multiple surgical interventions. Curative treatment inducing immunological tolerance in formerly sensitized patients is experimental and not yet genera...

Natural rubber latex allergy.

Immediate hypersensitivity to natural rubber latex (NRL) has become increasingly common during the last 20 years. It is currently one of the most frequently encountered occupational diseases among the healthcare workers and a problem even in other occupations where protective gloves are used. Several groups at high risk for developing NRL allergy have been defined, including healthcare workers ...

Evaluation of a dipstick test (Allergodip-Latex) for in vitro diagnosis of natural rubber latex allergy.

BACKGROUND IgE-mediated hypersensitivity to latex has been recognized as an increasing health problem with far-reaching consequences for patients, regarding both their occupational situation and safety in medical care. Therefore, a correct diagnosis of natural rubber latex (NRL) allergy is essential. The purpose of the study was to evaluate sensitivity and specificity of several established dia...